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pentobarbital will decrease the extent or impact of nilotinib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check.pentobarbital improves effects of ifosfamide by impacting hepatic enzyme CYP2B6 metabolism. Use Warning/Check. Coadministration of ifosfamide with CYP2B6 inducers may enhance metabolism of ifosfamide to its metab